Proyectos

44639772860. Fondecyt Regular (Chile): Principal investigator (N^o 1190652). “Expanding the multi–target neuroprotective chemical space of benzofuran scaffolds from fungal and synthetic sources: establishing the basis for drug development in Alzheimer’s disease”. Universidad del Bio – Bio, Concepción, Chile (305'000 USD). 2019 - 2022.
44639772861. Concurso Nacional de Atracción de Capital Humano Avanzado del Extranjero Modalidad de Estadías Cortas: Principal investigator (MEC80190048). “Antimicrobial activity on multi resistant bacteria and neuroprotective effect on Alzheimer’ disease of fungi isolated from Andean-Patagonian environments in the south of Chile”. Universidad del Bio – Bio, Concepción, Chile (15'000 USD). 2020 - 2022.
44639772862. VRID-UDEC, Interdisciplinary Research Grants. Associate investigator (N^o 2019.254). "Synthesis and biological evaluation of Chalcone-benzodihydrofuran hybrid cores". Universidad de Concepción, Concepción, Chile (10'000 USD). 2019 - 2021.
44639772863. Marie Curie Fellowship: Principal investigator (N^o 655856). "Discovery of novel β-lactam analogs oriented to control multidrug-resistant bacteria enabled by Pd-catalyzed C–H activation of aliphatic amines" . University of Cambridge, Cambridge, UK (40,000 USD) 2014 – 2016.

Publicaciones

1. Montavon, T. J.; Li, J.; Cabrera-Pardo, J. R.; Mrksich, M.; Kozmin, S. A. Three Component Reaction Discovery Enabled by Mass Spectrometry of Self-Assembled Monolayers. Nature Chemistry 2012, 4, 45-51.
2. Cabrera-Pardo, J. R.; Chai, D. I.; Liu, S.; Mrksich, M.; Kozmin, S. A; Label-Assisted Mass Spectrometry for the Acceleration of Reaction Discovery and Optimization. Nature Chemistry 2013, 5, 423-427. (Highlighted in C&EN)
3. Cabrera-Pardo, J. R.; Chai, D. I.; Kozmin, S. A; Silver-Promoted Benzannulations of Siloxy Alkynes with Pyridinium and Isoquinolinium Salts. Advanced Synthesis & Catalysis 2013, 355, 2495-2498.
4. Paz, C.; Becerra, J.; Silvia, M.; Cabrera-Pardo, J.R.; Burgos, V.; Heydenreich, M.; Schmidt, B. (-)-8-Oxohobartine a New Indole Alkalod from Aristotelia chilensis (Mol.) Stuntz. Records of Natural Products 2016, 10, 68-73.
5. Torres, S; Cabrera-Pardo, J. R.; Alonso, F.; Bustos, E.; Pérez, C.; Palfner, G.; Hernández, V.; Uriarte, E.; Becerra, J. Changes in Secondary Metabolites Profiles and Biological Activity of the Fresh Fruiting Bodies of Stereum hirsutum. Exposed to High-dose UV-B Radiation. Journal of The Chilean Chemical Society 2016, 4, 3224-3227.
6. Cabrera-Pardo, J. R.; Trowbridge, A.; Nappi, M; Ozaki, K.; Gaunt, M. J. Selective Pd(II)-Catalyzed Carbonylation of Methylene beta-C-H Bonds in Aliphatic Amines. Angewandte Chemie International Edition 2017, 56, 11958-11962.
7. Png, Z. M.; Cabrera-Pardo, J. R.; Peiró Cadahía, J.; Gaunt, M. J. Diastereoselective C–H carbonylative annulation of aliphatic amines: a rapid route to functionalized γ–lactams. Chemical Science 2018, 9, 7628-7633.
8. Gutiérrez, C.; Zenis, J.; Legarraga, P.; Cabrera-Pardo, J.R.; García, P.; Bello-Toledo, H; Opazo-Capurro, A.; González-Rocha, G. Genetic analysis of the first mcr-1 positive Escherichia coli isolate collected from an outpatient in Chile. The Brazilian Journal of Infectious Diseases 2019, 3, 203-206.
9. Torres, S.; González-Ramírez, M.; Gavilán, J.; Paz, C.; Palfner, G.; Arnold, N.; Fuentealba, J.; Becerra, J.; Pérez, C.*; Cabrera-Pardo, J.R.* Exposure to UVB radiation leads to increased deposition of cell-wall associated xerocomic acid in cultures of Serpula himantioides. Applied and Environmental Microbiology 2019, 85:e00870-19. (Corresponding Author).
10. Cabrera-Pardo, J.R.; Lood, R.; Udekwu, K.; González-Rocha, G.; Munita, J.M.; Järhult, J.D.*; Opazo-Capurro, A.* A One Health – One World initiative to control antibiotic resistance: a Chile - Sweden collaboration. One Health 2019, 8, 100100.
11. Méndez, P.; Nuñez, C.; Cabrera-Pardo, J.R.; Paz, C.; Barraza, J. M.; Castillo, R.; Peña Farfal, C. Adsorption ability of activated carbon obtained from sub-bituminous coal (Lebu, Chile) to capture trimethylamine. Journal of The Chilean Chemical Society 2019, 3, 4582-4585.
12. Figueroa, F. A.; Abdala-Díaz, R.; Hernández, V.; Pedreros, P.; Aranda, M.; Cabrera-Pardo, J. R.; Pérez, C.; Becerra, J.; Urrutia, R. Invasive diatom of Didymosphenia geminata as a source of polysaccharides with antioxidant and immunomodulatory effects on macrophage cell lines. Journal of Applied Phycology 2019. https://doi.org/10.1007/s10811-019-01976-6
13. Cabrera-Pardo, J.R.*; Fuentealba, J.*; Gavilán, J.; Cajas, D.; Becerra, J.; Napiórkowska, M. Exploring the multi–target neuroprotective chemical space of benzofuran scaffolds: a new strategy in drug development for Alzheimer’s disease. Frontiers in Pharmacology 2020, 10, 1679. (Corresponding Author).
14. Riquelme, C; Bernardo, C; Ruiz, D; Herrera, M; Becerra, J; Perez, C; Rajchenberg, M; Cabrera-Pardo, J.R. * The de novo production of halogenated hydroquinone metabolites by the new Andean-Patagonian white-rot fungus Phylloporia boldo Rajchenb & Pildain. Current Research in Environmental & Applied Mycology (Journal of Fungal Biology) 2020, 10, 198-205. (Corresponding Author).
15. Rhodes, Z; Cabrera-Pardo, J. R; Li, M; Minteer, S.D. Electrochemical Advances in Non?Aqueous Redox Flow Batteries. Israel Journal of Chemistry 2020. doi:10.1002/ijch.202000049
16. Li, M; Rhodes, Z; Cabrera-Pardo, J. R; Minteer, S.D. Recent advancements in rational design of non-aqueous organic redox flow batteries. Sustainable Energy Fuels 2020, 4, 4370-4389.